How do hydrocodone and oxycodone compared




















The majority of branded pharmaceuticals with these opioids contain 2. Geriatric dosage of oxycodone is 2. Neither drug is prescribed to children under 12 months of age. For older children, dosage depends on weight, with children who weigh less than pounds receiving. The maximum dosage daily for hydrocodone is 40mg per day, 80mg for oxycodone. If narcotic tolerance has been established in a medically-controlled environment, additional doses may be prescribed.

Additional studies addressing severe and chronic pain, as well as pain management for cancer patients and the elderly agree that both oxycodone and hydrocodone, when properly and similarly prescribed, deliver the same level and duration of pain relief. Some studies have analyzed the effects of combining these drugs with other pain relief medications, the two most common being acetaminophen, mentioned above, and ibuprofen.

In an NIH study that focused on pain management following gynecological surgeries, 7. As these drugs do come with a risk of dependency , finding lower-dose alternatives or combination therapies is sometimes preferable. Brand names and the combination of these drugs with other pharmaceuticals influence pricing. Cost also sometimes determines which medication is prescribed.

Oxycodone-using patients experience less overall side effects but may endure drowsiness, vomiting, nausea, itching, dizziness, headache, loss of appetite, stomach pain, dry mouth and mild to moderate constipation. The efficacy comparison studies also compared side effects like nausea and dizziness. There was no significant indication that one drug delivered worse effects than the other; however constipation was elevated somewhat in the hydrocodone test group.

For both drugs, extreme nausea and vomiting can cause additional problems such as dehydration. Combining oxycodone or hydrocodone with alcohol may cause serious injury or death. Both may impair driving and equipment operation, and result in falls from dizziness. Both medications are known to react negatively to some herbal and vitamin supplements, depression and anxiety medications, sleeping pills, muscle relaxants, and various other pain meds. Oxycodone efficacy may be hindered by grapefruit products.

Oxycodone is a category B drug in the U. Many doctors will prescribe oxycodone to pregnant women only in cases where the benefit to mother outweighs the potential risk to the fetus.

It is worth noting that Australia lists oxycodone as a category C drug in its healthcare system, meaning there oxycodone is "suspected of causing harmful effects," though these may be reversible — as in the case of potential withdrawal symptoms — and do not include malformations. However, people who abuse opioids will break, crush, chew, dissolve or snort OxyContin to get the full effects of the drug all at once.

Even though OxyContin is designed with abuse-deterrent features, there is still an abuse risk. Oxycodone is intended to relieve chronic pain or cancer-related pain. Oxycodone, like hydrocodone, is a central nervous system depressant. Someone who uses oxycodone may show side effects including:. When you look at hydrocodone vs.

Both are Schedule II controlled substance with a high abuse and dependence potential. Both are central nervous system depressants, and both have the potential to cause euphoria when high doses are used. Both are also prescription pain relievers. Both hydrocodone and oxycodone are often identified as the drugs of choice by people who abuse opioids. When comparing hydrocodone vs. Oxycodone does tend to have more of an abuse potential, however.

The dosages of hydrocodone and oxycodone are similar, as are the side effects. Oxycodone is usually more expensive than hydrocodone, both in pharmacies and on-the-streets. Both hydrocodone and oxycodone have not only an addiction potential but can and do lead to fatal overdoses. Signs of an overdose related to either hydrocodone or oxycodone can include:. With so many similarities, the only real significant difference in hydrocodone vs.

Both drugs are addictive, but oxycodone is likely more addictive than hydrocodone. Schedule II drugs have a high potential for being misused.

Frequently, both oxycodone and hydrocodone are combined with other painkillers or chemicals. Pure oxycodone is available in a brand name drug called Oxycontin. You take Oxycontin tablets orally usually every 12 hours. The tablets come in several different doses. The dose you use depends on the severity of your pain. Pure hydrocodone is available in an extended-release form, which is designed to release into your body slowly, not all at once. This allows the medication to work over a long period of time.

The brand name for this drug is Zohydro ER. You can take a capsule orally every 12 hours. This medication can be used to treat long-term pain problems. In the event of an emergency situation, researchers have found the two medications treat pain equally. In a study with both drugs, researchers found that both oxycodone and hydrocodone were equally effective at treating pain caused by fractures.

Participants experienced equal pain relief 30 and 60 minutes after the medication was taken. However, those who were given hydrocodone experienced constipation more frequently than participants who used oxycodone. Another study found that the combination of oxycodone and acetaminophen was 1. Both oxycodone and hydrocodone are sold as brand-name drugs and as generic alternatives.

Generic medications are cheaper than their brand-name counterparts. For that reason, you may wish to try the generic versions. Before you do that, consult your doctor. Some generic versions of medications have different ratios of active and inactive ingredients. To be classified as generic by the U. Food and Drug Administration, the drug must include the same strength of active ingredients, but may not have the same amount of inactive ingredients. If you need to use the brand name but find that the price tag is too high, prescription drug insurance and prescription coupons may help reduce your total cost.

The most common side effects of oxycodone and hydrocodone are similar. These side effects include:. Oxycodone is more likely to cause side effects of dizziness and drowsiness, as well as fatigue, headaches, and feelings of euphoria. Hydrocodone is more likely to cause constipation and stomach pain. People who have asthma or breathing difficulties may need to avoid these pain medications entirely.

Also, because of the risk of increased constipation, people who have blockages or difficulty with constipation may not want to take oxycodone or hydrocodone. These drugs can make these conditions worse. The combination of alcohol and painkillers can cause extreme dizziness or drowsiness. The combination can also damage your liver. A study published in the American Journal of Obstetrics and Gynecology found that there was an association between opioid treatment and certain birth defects.



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