Advertising revenue supports our not-for-profit mission. This content does not have an English version. This content does not have an Arabic version. Overview Familial hypercholesterolemia affects the way the body processes cholesterol. Request an Appointment at Mayo Clinic. Share on: Facebook Twitter. Show references Kliegman RM, et al. Defects in metabolism of lipids. In: Nelson Textbook of Pediatrics. Elsevier; Accessed July 15, Goldman L, et al.
These send information about how our site is used to a service called Google Analytics. We use this information to improve our site. Let us know if this is OK. You can read more about our cookies before you choose. Change my preferences I'm OK with analytics cookies. People with FH have elevated LDL cholesterol levels from birth and children with FH show an increased thickness of their arteries compared to their non-FH siblings by the age of 11, showing the process of atherosclerosis development starts early in life.
The NICE FH guideline has recommended case finding in primary care using electronic records as an acceptable and highly cost-effective method for individual practices to identify patients who so far did not have the benefit of treatment. A DNA test is used to provide an unequivocal diagnosis for a patient with a clinical diagnosis of FH. We anticipate that this will be fully operational from April Causes of High Cholesterol. Prevention and Treatment of High Cholesterol. Cholesterol Tools and Resources.
Cholesterol Podcasts. Familial Hypercholesterolemia, FH for short, is an inherited disorder that leads to aggressive and premature cardiovascular disease. With this series of podcasts you will learn really what FH is, how to manage it. Inheriting issues with cholesterol Familial hypercholesterolemia FH is an inherited defect in how the body recycles LDL bad cholesterol.
How common is it? If left untreated, people with FH typically develop coronary heart disease. Treating FH FH remains underdiagnosed and undertreated. Last Reviewed: Nov 9, Cholesterol Podcasts Familial Hypercholesterolemia, FH for short, is an inherited disorder that leads to aggressive and premature cardiovascular disease.
FH is not caused by diet or lifestyle. The result is very high LDL-C levels the body that the body can not remove. Left untreated, high LDL-C levels can lead to early cardiovascular disease. The good news: Early diagnosis and treatment reduces the risk of heart disease so that people with FH can have a normal life expectancy. Most cholesterol circulating in the body is produced by the liver and is a necessary component in the structure and function of human cells. Individuals with FH are unable to recycle this natural supply of cholesterol that their bodies are constantly producing.
FH begins at birth and if is left untreated can cause severe cardiovascular events such as heart attacks, strokes and even narrowing of the heart valves at early age.
FH is diagnosed based on a physical exam by your family doctor and lab tests. Your doctor will look for any types of fatty deposits or lensions that are a result of very high cholesterol.
Your doctor will also ask about your medical and family history. Your doctor will need to rule out other causes for increased cholesterol including: renal dysfunction, hepatic disease, diabetes, hypothyroidism, obesity, cigarette smoking and alcohol, and use of some medications, including oral contraceptives. Lab tests include a blood test to check your cholesterol levels.
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